Pharmacokinetics of orally administered ABT-751 in children with neuroblastoma and other solid tumors

PURPOSE: To describe the pharmacokinetics of orally administered ABT-751 and its conjugated metabolites in children with neuroblastoma and other solid tumors and to relate pharmacokinetic parameters to toxicity and therapeutic outcomes. METHODS: Patients (median age, 11 years) with neuroblastoma (n...

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Gepubliceerd in:Cancer Chemother Pharmacol
Hoofdauteurs: Fox, Elizabeth, Maris, John M., Cohn, Susan L., Goodspeed, Wendy, Goodwin, Anne, Kromplewski, Marie, Medina, Diane, Xiong, Hao, Krivoshik, Andrew, Widemann, Brigitte, Adamson, Peter C., Balis, Frank M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936731/
https://ncbi.nlm.nih.gov/pubmed/20044751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1218-z
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