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5-HT(2A) receptor activation normalizes stress-induced dysregulation of GABAergic signaling in the ventral tegmental area
Stress is known to alter GABAergic signaling in the ventral tegmental area (VTA), and this inhibitory plasticity is associated with increased alcohol self-administration. In humans, serotonin 2A receptor (5-HT(2A)R) agonists can treat stress- and alcohol-related disorders, but the neural substrates...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6936697/ https://ncbi.nlm.nih.gov/pubmed/31806759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911446116 |
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