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Loss of p57(KIP2) expression confers resistance to contact inhibition in human androgenetic trophoblast stem cells
A complete hydatidiform mole (CHM) is androgenetic in origin and characterized by enhanced trophoblastic proliferation and the absence of fetal tissue. In 15 to 20% of cases, CHMs are followed by malignant gestational trophoblastic neoplasms including choriocarcinoma. Aberrant genomic imprinting may...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6936680/ https://ncbi.nlm.nih.gov/pubmed/31792181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916019116 |
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