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Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
Autoimmune uveoretinitis is a significant cause of visual loss, and mouse models offer unique opportunities to study its disease mechanisms. Aire(−/−) mice fail to express self-antigens in the thymus, exhibit reduced central tolerance, and develop a spontaneous, chronic, and progressive uveoretiniti...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6936593/ https://ncbi.nlm.nih.gov/pubmed/31843893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915571116 |
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