A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na(+)/I(−) Symporter

The Na(+)/iodide (I(−)) symporter (NIS), a glycoprotein expressed at the basolateral plasma membrane of thyroid follicular cells, mediates I(−) accumulation for thyroid hormonogenesis and radioiodide therapy for differentiated thyroid carcinoma. However, differentiated thyroid tumors often exhibit l...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Martín, Mariano, Modenutti, Carlos Pablo, Peyret, Victoria, Geysels, Romina Celeste, Darrouzet, Elisabeth, Pourcher, Thierry, Masini-Repiso, Ana María, Martí, Marcelo Adrián, Carrasco, Nancy, Nicola, Juan Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936561/
https://ncbi.nlm.nih.gov/pubmed/30496374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00603
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