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T cell receptor specificity drives accumulation of a reparative population of regulatory T cells within acutely injured skeletal muscle

Foxp3(+)CD4(+) regulatory T cells (Tregs) play important roles in controlling both homeostatic processes and immune responses at the tissue and organismal levels. For example, Tregs promote muscle regeneration in acute or chronic injury models by direct effects on local muscle progenitor cells, as w...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Cho, Jun, Kuswanto, Wilson, Benoist, Christophe, Mathis, Diane
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936428/
https://ncbi.nlm.nih.gov/pubmed/31822623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914848116
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