Cellular and molecular characterization of multiplex autism in human induced pluripotent stem cell-derived neurons

BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with pronounced heritability in the general population. This is largely attributable to the effects of polygenic susceptibility, with inherited liability exhibiting distinct sex differences in phenotypic expression. Attempts...

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Publicat a:Mol Autism
Autors principals: Lewis, Emily M. A., Meganathan, Kesavan, Baldridge, Dustin, Gontarz, Paul, Zhang, Bo, Bonni, Azad, Constantino, John N., Kroll, Kristen L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936127/
https://ncbi.nlm.nih.gov/pubmed/31893020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-019-0306-0
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