Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

Cortical interneurons (cINs) modulate excitatory neuronal activity by providing local inhibition. During fetal development, several cIN subtypes derive from the medial ganglionic eminence (MGE), a transient ventral telencephalic structure. While altered cIN development contributes to neurodevelopmen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Meganathan, Kesavan, Lewis, Emily M. A., Gontarz, Paul, Liu, Shaopeng, Stanley, Edouard G., Elefanty, Andrew G., Huettner, James E., Zhang, Bo, Kroll, Kristen L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748186/
https://ncbi.nlm.nih.gov/pubmed/29229852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712365115
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