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Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells

BACKGROUND: Ticagrelor and clopidogrel, P2Y(12) receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in which inflammation is involved. Moreover, NF-B is the central regulator of i...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: Jia, Zhuyin, Huang, Yiwei, Ji, Xiaojun, Sun, Jiaju, Fu, Guosheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936058/
https://ncbi.nlm.nih.gov/pubmed/31888640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-019-01287-1
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