DHA and EPA Down-regulate COX-2 Expression through Suppression of NF-κB Activity in LPS-treated Human Umbilical Vein Endothelial Cells

Inflammatory processes of vascular endothelial cells play a key role in the development ofatherosclerosis. We determined the anti-inflammatory effects and mechanisms of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on LPS-treated human umbilical vein endothelial cells (HUVECs) to evalua...

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Detalhes bibliográficos
Main Authors: Lee, Soon Ae, Kim, Hye Jung, Chang, Ki Churl, Baek, Jong Chul, Park, Ji Kwon, Shin, Jeong Kyu, Choi, Won Jun, Lee, Jong Hak, Paik, Won Young
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766710/
https://ncbi.nlm.nih.gov/pubmed/19885014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.4.301
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