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Estimating viral bottleneck sizes for FMDV transmission within and between hosts and implications for the rate of viral evolution

RNA viruses exist as populations of closely related genomes, characterized by a high diversity of low-frequency variants. As viral genomes from one population disperse to establish new sites of replication, the fate of these low-frequency variants depends to a large extent on the size of the foundin...

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Bibliografische gegevens
Gepubliceerd in:Interface Focus
Hoofdauteurs: Orton, Richard J., Wright, Caroline F., King, Donald P., Haydon, Daniel T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936012/
https://ncbi.nlm.nih.gov/pubmed/31897294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2019.0066
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