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Circulating Virus Load Determines the Size of Bottlenecks in Viral Populations Progressing within a Host

For any organism, population size, and fluctuations thereof, are of primary importance in determining the forces driving its evolution. This is particularly true for viruses—rapidly evolving entities that form populations with transient and explosive expansions alternating with phases of migration,...

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Main Authors: Gutiérrez, Serafín, Yvon, Michel, Pirolles, Elodie, Garzo, Eliza, Fereres, Alberto, Michalakis, Yannis, Blanc, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486874/
https://ncbi.nlm.nih.gov/pubmed/23133389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003009
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