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Reciprocal actions of constrictor prostanoids and superoxide in chronic hypoxia-induced pulmonary hypertension: roles of EETs

Epoxyeicosatrienoic acids (EETs) are synthesized from arachidonic acid by CYP/epoxygenase and metabolized by soluble epoxide hydrolase (sEH). Roles of EETs in hypoxia-induced pulmonary hypertension (HPH) remain elusive. The present study aimed to investigate the underlying mechanisms, by which EETs...

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Pubblicato in:Pulm Circ
Autori principali: Kandhi, Sharath, Alruwaili, Norah, Wolin, Michael S, Sun, Dong, Huang, An
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935883/
https://ncbi.nlm.nih.gov/pubmed/31908769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894019895947
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