Nuclear up regulation of the BRCA1-associated ubiquitinase BAP1 is associated with tumor aggressiveness in prostate cancers lacking the TMPRSS2:ERG fusion

Loss of the putative tumor suppressor BAP1 is a candidate biomarker for adverse prognosis in many cancer types, but conversely for improved survival in others. Studies on the expression and prognostic role of BAP1 in prostate cancer are currently lacking. We used a tissue microarray of 17,747 indivi...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Steurer, Stefan, Schwemmer, Lara, Hube-Magg, Claudia, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Clauditz, Till S., Luebke, Andreas M., Simon, Ronald, Sauter, Guido, Izbicki, Jakob, Schroeder, Cornelia, Schlomm, Thorsten, Huland, Hartwig, Heinzer, Hans, Haese, Alexander, Graefen, Markus, Göbel, Cosima, Weidemann, Sören, Lebok, Patrick, Dum, David, Fraune, Christoph, Minner, Sarah, Meiners, Jan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935259/
https://ncbi.nlm.nih.gov/pubmed/31903168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27270
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