High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

BACKGROUND: Protein tyrosine phosphatase non-receptor 12 (PTPN12) is ubiquitously tyrosine phosphatase with tumor suppressive properties. METHODS: PTPN12 expression was analyzed by immunohistochemistry on a tissue microarray with 13,660 clinical prostate cancer specimens. RESULTS: PTPN12 staining wa...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Weidemann, Sören A., Sauer, Charlotte, Luebke, Andreas M., Möller-Koop, Christina, Steurer, Stefan, Hube-Magg, Claudia, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Clauditz, Till S., Simon, Ronald, Sauter, Guido, Göbel, Cosima, Lebok, Patrick, Dum, David, Fraune, Christoph, Kind, Simon, Minner, Sarah, Izbicki, Jakob, Schlomm, Thorsten, Huland, Hartwig, Heinzer, Hans, Burandt, Eike, Haese, Alexander, Graefen, Markus, Heumann, Asmus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790047/
https://ncbi.nlm.nih.gov/pubmed/31606028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6182-3
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