High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

BACKGROUND: Protein tyrosine phosphatase non-receptor 12 (PTPN12) is ubiquitously tyrosine phosphatase with tumor suppressive properties. METHODS: PTPN12 expression was analyzed by immunohistochemistry on a tissue microarray with 13,660 clinical prostate cancer specimens. RESULTS: PTPN12 staining wa...

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發表在:BMC Cancer
Main Authors: Weidemann, Sören A., Sauer, Charlotte, Luebke, Andreas M., Möller-Koop, Christina, Steurer, Stefan, Hube-Magg, Claudia, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Clauditz, Till S., Simon, Ronald, Sauter, Guido, Göbel, Cosima, Lebok, Patrick, Dum, David, Fraune, Christoph, Kind, Simon, Minner, Sarah, Izbicki, Jakob, Schlomm, Thorsten, Huland, Hartwig, Heinzer, Hans, Burandt, Eike, Haese, Alexander, Graefen, Markus, Heumann, Asmus
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790047/
https://ncbi.nlm.nih.gov/pubmed/31606028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6182-3
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