High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

BACKGROUND: Protein tyrosine phosphatase non-receptor 12 (PTPN12) is ubiquitously tyrosine phosphatase with tumor suppressive properties. METHODS: PTPN12 expression was analyzed by immunohistochemistry on a tissue microarray with 13,660 clinical prostate cancer specimens. RESULTS: PTPN12 staining wa...

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Publicat a:BMC Cancer
Autors principals: Weidemann, Sören A., Sauer, Charlotte, Luebke, Andreas M., Möller-Koop, Christina, Steurer, Stefan, Hube-Magg, Claudia, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Clauditz, Till S., Simon, Ronald, Sauter, Guido, Göbel, Cosima, Lebok, Patrick, Dum, David, Fraune, Christoph, Kind, Simon, Minner, Sarah, Izbicki, Jakob, Schlomm, Thorsten, Huland, Hartwig, Heinzer, Hans, Burandt, Eike, Haese, Alexander, Graefen, Markus, Heumann, Asmus
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790047/
https://ncbi.nlm.nih.gov/pubmed/31606028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6182-3
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