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NPM1 Exhibits Structural and Dynamic Heterogeneity upon Phase Separation with the p14ARF Tumor Suppressor

Nucleophosmin (NPM1) is an abundant nucleolar protein that aids in the maturation of pre-ribosomal particles and participates in oncogenic stress responses through its interaction with the Alternative Reading Frame tumor suppressor (p14ARF). NPM1 mediates multiple mechanisms of phase separation whic...

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Vydáno v:J Magn Reson
Hlavní autoři: Gibbs, Eric, Perrone, Barbara, Hassan, Alia, Kümmerle, Rainer, Kriwacki, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934896/
https://ncbi.nlm.nih.gov/pubmed/31751897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2019.106646
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