Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis

Nonalcoholic fatty liver disease (NAFLD) is becoming a major etiological risk factor for hepatocellular carcinoma (HCC) in the United States and other Western countries. In this study, we investigated the role of gene-specific promoter cytosine DNA methylation and gene expression alterations in the...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Borowa-Mazgaj, Barbara, de Conti, Aline, Tryndyak, Volodymyr, Steward, Colleen R, Jimenez, Leandro, Melnyk, Stepan, Seneshaw, Mulugeta, Mirshahi, Faridodin, Rusyn, Ivan, Beland, Frederick A, Sanyal, Arun J, Pogribny, Igor P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934890/
https://ncbi.nlm.nih.gov/pubmed/31086990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz110
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