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The mechanism of MYB transcriptional regulation by MLL-AF9 oncoprotein
Acute leukaemias express high levels of MYB which are required for the initiation and maintenance of the disease. Inhibition of MYB expression or activity has been shown to suppress MLL-fusion oncoprotein-induced acute myeloid leukaemias (AML), which are among the most aggressive forms of AML, and i...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934848/ https://ncbi.nlm.nih.gov/pubmed/31882723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56426-7 |
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