Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research

Cancer research requires models closely resembling the tumor in the patient. Human tissue cultures can overcome interspecies limitations of animal models or the loss of tissue architecture in in vitro models. However, analysis of tissue slices is often limited to histology. Here, we demonstrate that...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haehnel, Susann, Reiche, Kristin, Loeffler, Dennis, Horn, Andreas, Blumert, Conny, Puppel, Sven-Holger, Kaiser, Nicole, Rapp, Felicitas, Rade, Michael, Horn, Friedemann, Meixensberger, Juergen, Bechmann, Ingo, Gaunitz, Frank, Winter, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934722/
https://ncbi.nlm.nih.gov/pubmed/31882946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56509-5
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