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Effective lung-targeted RNAi in mice with peptide-based delivery of nucleic acid

We have previously developed efficient peptide-based nucleic acid delivery vectors PF14 and NF55, where we have shown that these vectors preferentially transfect lung tissue upon systemic administration with the nucleic acid. In the current work, we have explored the utilization and potential of the...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Kurrikoff, Kaido, Freimann, Krista, Veiman, Kadi-Liis, Peets, Elin Madli, Piirsoo, Andres, Langel, Ülo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934651/
https://ncbi.nlm.nih.gov/pubmed/31882941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56455-2
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