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Effective lung-targeted RNAi in mice with peptide-based delivery of nucleic acid

We have previously developed efficient peptide-based nucleic acid delivery vectors PF14 and NF55, where we have shown that these vectors preferentially transfect lung tissue upon systemic administration with the nucleic acid. In the current work, we have explored the utilization and potential of the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kurrikoff, Kaido, Freimann, Krista, Veiman, Kadi-Liis, Peets, Elin Madli, Piirsoo, Andres, Langel, Ülo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934651/
https://ncbi.nlm.nih.gov/pubmed/31882941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56455-2
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