Nested PCR and the TaqMan SNP Genotyping Assay enhanced the sensitivity of drug resistance testing of Mycobacterium leprae using clinical specimens of leprosy patients

BACKGROUND: Although leprosy is efficiently treated by multidrug therapy, resistance to first-line (dapsone, rifampin) and second-line (fluoroquinolones) drugs has been described worldwide. However, the characteristics of drug resistance in Southwest China remain unknown. Furthermore, the sensitivit...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Chen, Xiaohua, He, Jun, Liu, Jian, You, Yuangang, Yuan, Lianchao, Wen, Yan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934270/
https://ncbi.nlm.nih.gov/pubmed/31881061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007946
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