GPR101 mediates the pro-resolving actions of RvD5(n-3 DPA) in arthritis and infections

N-3 docosapentaenoic acid–derived resolvin D5 (RvD5(n-3) (DPA)) is diurnally regulated in peripheral blood and exerts tissue-protective actions during inflammatory arthritis. Here, using an orphan GPCR screening approach coupled with functional readouts, we investigated the receptor(s) involved in m...

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Publicat a:J Clin Invest
Autors principals: Flak, Magdalena B., Koenis, Duco S., Sobrino, Agua, Smith, James, Pistorius, Kimberly, Palmas, Francesco, Dalli, Jesmond
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934227/
https://ncbi.nlm.nih.gov/pubmed/31793912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131609
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