Resolving Inflammation: Synthesis, Configurational Assignment and Biological Evaluations of RvD1(n-3 DPA)

New drugs that can resolve inflammation without immunosuppressive effects are at the medicinal chemistry frontier. Pro-resolving endogenously formed small molecules, i.e. the resolvins, are excellent candidates displaying such bioactions. The first total synthesis of the specialized pro-resolving me...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Tungen, Jørn Eivind, Gerstmann, Lisa, Vik, Anders, De Matteis, Roberta, Colas, Romain Alexandre, Dalli, Jesmond, Chiang, Nan, Serhan, Charles Nicholas, Kalesse, Markus, Hansen, Trond Vidar
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368681/
https://ncbi.nlm.nih.gov/pubmed/30511787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201806029
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