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Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

Alterations in gut microbiota impact the pathophysiology of several diseases, including cancer. Radiotherapy (RT), an established curative and palliative cancer treatment, exerts potent immune modulatory effects, inducing tumor-associated antigen (TAA) cross-priming with antitumor CD8(+) T cell elic...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Uribe-Herranz, Mireia, Rafail, Stavros, Beghi, Silvia, Gil-de-Gómez, Luis, Verginadis, Ioannis, Bittinger, Kyle, Pustylnikov, Sergey, Pierini, Stefano, Perales-Linares, Renzo, Blair, Ian A., Mesaros, Clementina A., Snyder, Nathaniel W., Bushman, Frederic, Koumenis, Constantinos, Facciabene, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934221/
https://ncbi.nlm.nih.gov/pubmed/31815742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124332
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