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New Findings in the Signaling Pathways of cis and trans Platinum Iodido Complexes’ Interaction with DNA of Cancer Cells

[Image: see text] We have selected a series of aliphatic amine platinum compounds bearing chloride and/or iodide as the leaving groups. The complexes’ cytotoxicity and interaction with DNA indicated differences in the reactivity. Now, we are reporting on the analysis of their molecular mechanism of...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Quiroga, Adoración G., Cama, Marta, Pajuelo-Lozano, Natalia, Álvarez-Valdés, Amparo, Sanchez Perez, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933576/
https://ncbi.nlm.nih.gov/pubmed/31891063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02831
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