Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors

AIMS: Sex differences in cardiac fibrosis point to the regulatory role of 17β-Estradiol (E2) in cardiac fibroblasts (CF). We, therefore, asked whether male and female CF in rodent and human models are differentially susceptible to E2, and whether this is related to sex-specific activation of estroge...

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Publicado en:Cardiovasc Res
Main Authors: Dworatzek, Elke, Mahmoodzadeh, Shokoufeh, Schriever, Cindy, Kusumoto, Kana, Kramer, Lisa, Santos, Gabriela, Fliegner, Daniela, Leung, Yuet-Kin, Ho, Shuk-Mei, Zimmermann, Wolfram-Hubertus, Lutz, Susanne, Regitz-Zagrosek, Vera
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933535/
https://ncbi.nlm.nih.gov/pubmed/30016401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy185
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