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DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains

Responses to a high fat, high sucrose (HFHS) diet vary greatly among inbred strains of mice. We sought to examine the epigenetic (DNA methylation) changes underlying these differences as well as variation in weight loss when switched to a low-fat chow diet. We surveyed DNA methylation from livers of...

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Publié dans:Front Endocrinol (Lausanne)
Auteurs principaux: Edillor, Chantle R., Parks, Brian W., Mehrabian, Margarete, Lusis, Aldons J., Pellegrini, Matteo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933503/
https://ncbi.nlm.nih.gov/pubmed/31920990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00882
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