DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains

Responses to a high fat, high sucrose (HFHS) diet vary greatly among inbred strains of mice. We sought to examine the epigenetic (DNA methylation) changes underlying these differences as well as variation in weight loss when switched to a low-fat chow diet. We surveyed DNA methylation from livers of...

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Publicat a:Front Endocrinol (Lausanne)
Autors principals: Edillor, Chantle R., Parks, Brian W., Mehrabian, Margarete, Lusis, Aldons J., Pellegrini, Matteo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Endocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933503/
https://ncbi.nlm.nih.gov/pubmed/31920990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00882
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