Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation

Autoimmune destruction of pancreatic beta cells causes absolute insulin deficiency and results in type 1 diabetes mellitus (T1DM). The substitution of healthy pancreatic beta cells for damaged cells would be the ideal treatment for T1DM; thus, the generation of pancreatic beta cells from adult stem...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Gao, Yuhua, Zhang, Ranxi, Dai, Shanshan, Zhang, Xue, Li, Xiangchen, Bai, Chunyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933421/
https://ncbi.nlm.nih.gov/pubmed/31921861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00351
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