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y+LAT1 and y+LAT2 contribution to arginine uptake in different human cell models: Implications in the pathophysiology of Lysinuric Protein Intolerance

y+LAT1 (encoded by SLC7A7), together with y+LAT2 (encoded by SLC7A6), is the alternative light subunits composing the heterodimeric transport system y+L for cationic and neutral amino acids. SLC7A7 mutations cause lysinuric protein intolerance (LPI), an inherited multisystem disease characterized by...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Rotoli, Bianca Maria, Barilli, Amelia, Visigalli, Rossana, Ferrari, Francesca, Dall’Asta, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933409/
https://ncbi.nlm.nih.gov/pubmed/31705628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14801
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