14‐3‐3ζ binds to and stabilizes phospho‐beclin 1(S295) and induces autophagy in hepatocellular carcinoma cells

Data from The Cancer Genome Atlas (TCGA) indicate that the expression levels of 14‐3‐3ζ and beclin 1 (a key molecule involved in cellular autophagy) are up‐regulated and positively correlated with each other (R = .5, P < .05) in HCC tissues. Chemoresistance developed in hepatoma cancer cells is a...

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Pubblicato in:J Cell Mol Med
Autori principali: Tang, Yufu, Zhang, Yibing, Liu, Shupeng, Sun, Zhongyi, Wang, Chunhui, Li, Longfei, Zhou, Wenping, Cheng, Shuqun
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933394/
https://ncbi.nlm.nih.gov/pubmed/31709727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14806
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