14-3-3ζ up-regulates hypoxia-inducible factor-1α in hepatocellular carcinoma via activation of PI3K/Akt/NF-кB signal transduction pathway

14-3-3ζ protein, a member of 14-3-3 family, plays important roles in multiple cellular processes. Our previous study showed that 14-3-3ζ could bind to regulate the expression of hypoxia-inducible factor-1α (HIF-1α), which is induced by hypoxia and a crucial factor for induction of tumor metastasis....

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Опубликовано в: :Int J Clin Exp Pathol
Главные авторы: Tang, Yufu, Lv, Pengfei, Sun, Zhongyi, Han, Lei, Luo, Bichao, Zhou, Wenping
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2015
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730068/
https://ncbi.nlm.nih.gov/pubmed/26884855
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