Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

The vascular endothelial growth factor receptor‐1 (VEGFR‐1) is a tyrosine kinase receptor frequently expressed in melanoma. Its activation by VEGF‐A or placental growth factor (PlGF) promotes tumour cell survival, migration and invasiveness. Moreover, VEGFR‐1 stimulation contributes to pathological...

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Publicado en:J Cell Mol Med
Autores principales: Atzori, Maria Grazia, Ceci, Claudia, Ruffini, Federica, Trapani, Mauro, Barbaccia, Maria Luisa, Tentori, Lucio, D'Atri, Stefania, Lacal, Pedro Miguel, Graziani, Grazia
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933379/
https://ncbi.nlm.nih.gov/pubmed/31758648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14755
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