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Down‐regulation of the mitochondrial i‐AAA protease Yme1L induces muscle atrophy via FoxO3a and myostatin activation

Muscle atrophy is closely associated with many diseases, including diabetes and cardiac failure. Growing evidence has shown that mitochondrial dysfunction is related to muscle atrophy; however, the underlying mechanisms are still unclear. To elucidate how mitochondrial dysfunction causes muscle atro...

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Publicat a:J Cell Mol Med
Autors principals: Lee, Yoo Jeong, Kim, Gyu Hee, Park, Sang Ick, Lim, Joo Hyun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933342/
https://ncbi.nlm.nih.gov/pubmed/31725201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14799
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