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Down‐regulation of the mitochondrial i‐AAA protease Yme1L induces muscle atrophy via FoxO3a and myostatin activation

Muscle atrophy is closely associated with many diseases, including diabetes and cardiac failure. Growing evidence has shown that mitochondrial dysfunction is related to muscle atrophy; however, the underlying mechanisms are still unclear. To elucidate how mitochondrial dysfunction causes muscle atro...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lee, Yoo Jeong, Kim, Gyu Hee, Park, Sang Ick, Lim, Joo Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933342/
https://ncbi.nlm.nih.gov/pubmed/31725201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14799
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