Identification of Fibrinogen as a Key Anti-apoptotic Factor in Human Fresh Frozen Plasma for Protecting Endothelial Cells in vitro

Resuscitation with human fresh frozen plasma (FFP) in hemorrhagic shock (HS) patients is associated with improved clinical outcomes. Our group has demonstrated that the beneficial effect of FFP is due to its blockade on endothelial hyperpermeability, thereby improving vascular barrier function. The...

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Pubblicato in:Shock
Autori principali: Yu, Qiang, Yang, Baibing, Davis, Joy M., Ghosn, Jean, Deng, Xiyun, Doursout, Marie-Francoise, Dong, Jing-fei, Wang, Run, Holcomb, John B., Wade, Charles E., Ko, Tien C., Cao, Yanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933102/
https://ncbi.nlm.nih.gov/pubmed/31454826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001399
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