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Identification of Fibrinogen as a Key Anti-apoptotic Factor in Human Fresh Frozen Plasma for Protecting Endothelial Cells in vitro

Resuscitation with human fresh frozen plasma (FFP) in hemorrhagic shock (HS) patients is associated with improved clinical outcomes. Our group has demonstrated that the beneficial effect of FFP is due to its blockade on endothelial hyperpermeability, thereby improving vascular barrier function. The...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Yu, Qiang, Yang, Baibing, Davis, Joy M., Ghosn, Jean, Deng, Xiyun, Doursout, Marie-Francoise, Dong, Jing-fei, Wang, Run, Holcomb, John B., Wade, Charles E., Ko, Tien C., Cao, Yanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933102/
https://ncbi.nlm.nih.gov/pubmed/31454826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001399
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