Andrographolide alleviates Parkinsonism in MPTP‐PD mice via targeting mitochondrial fission mediated by dynamin‐related protein 1

BACKGROUND AND PURPOSE: Accumulating evidence indicates that mitochondrial dynamics play an important role in the progressive deterioration of dopaminergic neurons. Andrographolide has been found to exert neuroprotective effects in several models of neurological diseases. However, the mechanism of h...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Geng, Ji, Liu, Wen, Gao, Jian, Jiang, Chunhong, Fan, Ting, Sun, Yang, Qin, Zheng‐Hong, Xu, Qiang, Guo, Wenjie, Gao, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932945/
https://ncbi.nlm.nih.gov/pubmed/31389613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14823
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