Nickel induces inflammatory activation via NF-κB, MAPKs, IRF3 and NLRP3 inflammasome signaling pathways in macrophages

Nickel (Ni), an environmental hazard, widely causes allergic contact hypersensitivity worldwide. Despite that Ni-stimulated pro-inflammatory response is vital in allergy, the underlying molecular mechanisms remain largely unclear. Here, we demonstrated that NiCl(2) activated nuclear factor kappa B (...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Guo, Hongrui, Liu, Huan, Jian, Zhijie, Cui, Hengmin, Fang, Jing, Zuo, Zhicai, Deng, Junliang, Li, Yinglun, Wang, Xun, Zhao, Ling, Geng, Yi, Ouyang, Ping, Lai, Weiming, Chen, Zhengli, Huang, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932914/
https://ncbi.nlm.nih.gov/pubmed/31822637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102570
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