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EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production
As a neurotropic virus, human Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease (HFMD) and may develop severe neurological disorders in infants. Toll-like receptor 7 (TLR7) acts as an innate immune receptor and is also a death receptor in the central nervous system (CNS). However, t...
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| Veröffentlicht in: | PLoS Pathog |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6932824/ https://ncbi.nlm.nih.gov/pubmed/31730654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008142 |
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