Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain

Proteostasis is critical for cells to maintain the balance between protein synthesis, quality control, and degradation. This is particularly important for myeloid cells of the central nervous system as their immunological function relies on proper intracellular protein turnover by the ubiquitin-prot...

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Опубликовано в: :Front Immunol
Главные авторы: Studencka-Turski, Maja, Çetin, Gonca, Junker, Heike, Ebstein, Frédéric, Krüger, Elke
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932173/
https://ncbi.nlm.nih.gov/pubmed/31921161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02900
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