Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain

Proteostasis is critical for cells to maintain the balance between protein synthesis, quality control, and degradation. This is particularly important for myeloid cells of the central nervous system as their immunological function relies on proper intracellular protein turnover by the ubiquitin-prot...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Studencka-Turski, Maja, Çetin, Gonca, Junker, Heike, Ebstein, Frédéric, Krüger, Elke
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932173/
https://ncbi.nlm.nih.gov/pubmed/31921161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02900
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