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Use of ECG Restitution (Beat‐to‐Beat QT‐TQ Interval Analysis) to Assess Arrhythmogenic Risk of QTc Prolongation with Guanfacine
BACKGROUND: Guanfacine (Intuniv) is a centrally active alpha‐2A adrenergic agonist for the new indication of attention‐deficit/hyperactivity disorder. QTc (QTcF and QTcNi) was prolonged at both therapeutic (4 mg) and supratherapeutic (8 mg) doses of a thorough QT study even though guanfacine has had...
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| Publicat a: | Ann Noninvasive Electrocardiol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6931917/ https://ncbi.nlm.nih.gov/pubmed/25200912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12202 |
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