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Comparing QT interval variability of semiautomated and high‐precision ECG methodologies in seven thorough QT studies—implications for the power of studies intended for definitive evaluation of a drug's QT effect

BACKGROUND: In studies of drug effects on electrocardiographic parameters, the level of precision in measuring QTc interval changes will influence a study's ability to detect small effects. METHODS: Variability data from investigational, placebo and moxifloxacin treatments from seven thorough Q...

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Detalhes bibliográficos
Publicado no:Ann Noninvasive Electrocardiol
Main Authors: Meiser, Karin, Jordaan, Pierre, Latypova, Sasha, Darpo, Borje
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6931460/
https://ncbi.nlm.nih.gov/pubmed/27995684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12416
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