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Comparing QT interval variability of semiautomated and high‐precision ECG methodologies in seven thorough QT studies—implications for the power of studies intended for definitive evaluation of a drug's QT effect
BACKGROUND: In studies of drug effects on electrocardiographic parameters, the level of precision in measuring QTc interval changes will influence a study's ability to detect small effects. METHODS: Variability data from investigational, placebo and moxifloxacin treatments from seven thorough Q...
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| Publié dans: | Ann Noninvasive Electrocardiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6931460/ https://ncbi.nlm.nih.gov/pubmed/27995684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/anec.12416 |
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