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The Somatic Mutation Hit on Top of Genetic APC mutations Cause Skin Tumor()
Inactivation of the adenomatous polyposis coli (APC) gene is the initiating event in familial adenomatous polyposis (FAP) patients. Up to 90% of FAP patients show intestinal tumors and other extracolonic malignancies including hepatoblastomas, desmoid tumors, and brain cancer. APC mutation mice (Apc...
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| Publié dans: | Transl Oncol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Neoplasia Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6931217/ https://ncbi.nlm.nih.gov/pubmed/31877462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.11.010 |
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