LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial–Mesenchymal Transition

Aerobic glycolysis is the main pathway for energy metabolism in cancer cells. It provides energy and biosynthetic substances for tumor progression and metastasis by increasing lactate production. Lactate dehydrogenase A (LDHA) promotes glycolysis process by catalyzing the conversion of pyruvate to l...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Cai, Hongshi, Li, Jiaxin, Zhang, Yadong, Liao, Yan, Zhu, Yue, Wang, Cheng, Hou, Jinsong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930919/
https://ncbi.nlm.nih.gov/pubmed/31921691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01446
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