Bavachin Protects Human Aortic Smooth Muscle Cells Against β-Glycerophosphate-Mediated Vascular Calcification and Apoptosis via Activation of mTOR-Dependent Autophagy and Suppression of β-Catenin Signaling

Vascular calcification is a major complication of cardiovascular disease and chronic renal failure. Autophagy help to maintain a stable internal and external environment that is important for modulating arteriosclerosis, but its pathogenic mechanism is far from clear. Here, we aimed to identify the...

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Publicado en:Front Pharmacol
Autores principales: He, Hu-Qiang, Law, Betty Yuen Kwan, Zhang, Ni, Qiu, Cong-ling, Qu, Yuan-Qing, Wu, An-Guo, Han, Yu, Song, Qi, Zheng, Wen-Lu, Liu, Yong, He, Yan-Zheng, Wong, Vincent Kam Wai
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930901/
https://ncbi.nlm.nih.gov/pubmed/31920640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01427
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